In the previous blog I wrote about my family tree with illustrious ancestors who had been a surgeon at the island Ameland. And that they would never have heard of DNA at that time. Which incidentally is obvious, because DNA was discovered in 1869.
Now, I also know little of DNA, other than that a small deviation has caused me Gastro Intestinal Stroma Tumors. And also that we all have a unique DNA that is the carrier of hereditary information. In many cases, GIST would not be inherited in a heritable way, although in certain patients there are strong indications that this is the case.
However, in my quest for positive impulses, DNA continued to stay in my mind and suddenly I realized why. A distant cousin of mine on Ameland, who descended in male line from the same ancestors, had ever participated in the Wadden DNA Project. That project has been started to find out, through DNA research, who had lived in the north of the Netherlands and the Frisian Wadden Islands in the past. In addition, the DNA is linked to the earliest known direct ancestors.
A visit to Wikipedia makes it clear that, for determining geographical origin, a method is available that looks only at the Y chromosome’s DNA (male sex chromosome). For my distant cousin (and me), was that when he participated in the study the grandson of that first Amlandse surgeon, born in 1632.
But from this same study were shown also three other people with a similar DNA background.
The “youngest” of it was one John (Johann) from N. Dorr, born in 1813. North Dorr appears to be a small town in the southwest of Michigan in the USA and probably he was originally an immigrant from Europe. Legally or illegally, that did not matter much at the time. Nice to know, but for our family tree, it did not brought me much further.
The following was Francis Kardel from 1665, Cork, Ireland. That was more intriguing, because this Francis was about 30 years younger than my ancestor and must have had another father. Unless he, at about 60 years of age, had moved form Ameland to Ireland to take care of some offspring over there. However it may be, there ever lived a still unknown pedigree branch in Ireland. After some more searching I found that this Kardel family, like so many Irish people, had also immigrated to the United States and settled in Michigan. The same state where John from 1813 was found.
However, the last person is the most interesting one. That was a Reginald Bynorthemore born in 1295 in Moretonhamps, Devon, England. The link from Devon to Ireland is not to difficult. But from Devon to Friesland?
But it is indeed a direct ancestor. Who himself, or one of his (grand)children, like a true visionary, saw a Brexit coming and and therefore decided (somewhere between 1300 and 1550), to leave England in a timely manner.
He also decided not to wait until North America became colonized, but saw the benefits of emigration to Friesland. And he was right. Because of that decision, my family could then grow at the island Ameland, whereby ultimately I came to the world. Which creates a family history that currently includes a period of more than 700 years.
Whathas this do to with about GIST? In fact, very little, except that the same DNA in which a deviating mutation has very unpleasant consequences to me, has also another positive side. And right there I was looking for.